the management of diabetes mellitus and late diabetic complicationsпокупайте товары для здоровья и красоты в интернет-магазине Salonfos.ru:
For the last few decades prevalence of diabetes mellitus is increasing alarmingly throughout the world with all its irreversible dreadful complications. Diabetic retinopathy is one of them and is a sight threatening condition. Along with hyperglycaemia in diabetic patients dyslipidaemia is one of the modifiable risk factors. Dyslipidaemia not only worsens preexisting endothelial dysfunction and injury but also may induce the same. With this idea in mind an attempt was made to evaluate the role of dyslipidaemia in the development of diabetic retinopathy in newly diagnosed type 2 diabetes mellitus. A case control study was done involving 85 newly diagnosed type 2 diabetes mellitus subjects with and without retinopathy. At the end of this work it was clearly evident that hyperglycaemia, hypertriglyceridaemia and low levels of HDL-C are associated with diabetic retinopathy. So intensified lipid lowering treatment strategy from the very beginning at diagnosis of diabetes might be beneficial in the prevention of diabetic retinopathy and other atherosclerosis related complications as vasculopathy plays the key role in all these chronic complications.
Diabetic retinopathy is a leading cause of blindness and is commonly viewed as a vascular complication of diabetes mellitus. However, diabetes mellitus causes visual dysfunction before the onset of clinically visible microvascular changes associated with diabetic retinopathy. Thus, viewing diabetic retinopathy more generally as a neurovascular disease may lead to an improved understanding of the mechanisms responsible for vision loss. This study reviews the impact of diabetes mellitus on inner and outer retinal visual and electrophysiologic function and advocates for a multimodal approach to the study of diabetic retinopathy
Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Here we focused on the epidemiology, late diabetic complications, association between diabetes mellitus and HCV infection and plasma protein profiling. Type 2 diabetes is most prevalent type and is more common in females. Above 70% diabetics had poor glycemic control along with one or more late diabetic complication(s) i.e. hypertensions, any grade of retinopathy and neuropathy. About 36.538% diabetic patients were reported to have HCV infection while in control group only 1.923% subjects were HCV positive by RT-PCR. Female diabetics have more risk to acquire HCV as compare to the male diabetic patients. Medical practices (hospitalization) play no role in nosocomial transmission of HCV in diabetic patients. Differences in the protein pattern were observed in low molecular weight proteins (5 to 35 kDa). Protein bands of 31kDa, 11kDa and 6.5kDa were missing in some diabetic HCV positive samples. Plasma protein profiling of diabetic patients by SDS-PAGE may be helpful to evaluate the disease state.
this book include complete description of a practical study done to reveal correlation between serum resistin levels with insulin resistance and severity of microangiopathy in type II diabetes mellitus. this book also try to declare debates arising about: Obesity and its relation to type II dabetes mellitus. Could resistin (the newly discovered hormone)be a link between obesity and type II diabetes mellitus? Relation between resistin and retinopathy, one of the most compromising diabetic complications.
Diabetes Mellitus is becomming a major epidemic worldwide and affects an estimated 16 million people in United States itself. As many as half of these are undiagnozed. Diabetes Mellitus epidemic has emerged during the later part of the twentieth century and continues unchecked in 21st century. Efforts are on to prevent the complications of Diabetes Mellitus and explore the status of micronutrients. To prevent and minimize the occurance of T2DM related complications in future, alteration in micronutrient status, expecially that of Magnesium, needs to be firmly looked into.
Diabetes mellitus has become a serious threat to public health throughout the world and there is a growing focus on the importance of medicinal plants and traditional health systems in treating the ailment. Medicinal herbs have been used by people for longer than we have been keeping written record and many studies have confirmed the benefits of these herbs with hypoglycemic effects in the management of diabetes. Herbal formulations are getting more importance in the treatment of diabetes because of their significant therapeutic effect, lesser side effects and cost effectiveness. This monograph emphasized the importance and utility of the herbs with potential anti-diabetic activity in the management of diabetes, based on the physiological mechanisms of the malady. All the drugs discussed in this monograph have exhibited significant pharmacological activity and hold definite promises in the management of Diabetes mellitus.
Diabetes is one of the main non-communicable diseases prevalent in Libya. The main features includes diabetic complications related to advanced glycation products. The onset of diabetic complications particularly nephropathy reflected by microalbuminuria and glycated hemoglobin (GHb) as a marker of non-enzymatic glycation reflect the presence of such complications in the local diabetic population.
Oxidative Stress and Diabetic Complications In diabetes mellitus,persistence of hyperglycemia was reported to cause increased production of oxidative parameters as well as defects in antioxidant defence system.Both factors possibly related to the pathogenesis of diabetic complications.Appropriate evaluation of oxidative stress(lipid peroxidation,protein oxidation and antioxidant status)will be beneficial in the regular evaluation of type I DM pediatric patients together with the routine laboratory assessment.
Diabetes mellitus is a complex disease requiring extensive strategies for effective management. Self-management of diabetes can be expensive and challenging for low-income patients. Current diabetes education and management programs largely target persons with higher levels of formal education and incomes. Kemper, Savage, Niederbaumer, and Anthony (2005) explored differences in knowledge about diabetes among low-income persons who had varying levels of formal education. The present study proposes to extend Kemper et al.’s study to examine the predictive relationship between diabetes self-management knowledge and level of formal education on depressive symptoms in low-income persons with diabetes mellitus. Results may guide nurses in designing effective diabetic education for low income persons who have varying degrees of depression symptoms and varying degrees of diabetes self-management knowledge.
Diabetes mellitus (DM) , is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period, associated with various complication. Globally, as of 2013, an estimated 382 million people have diabetes worldwide, with type 2 diabetes making up about 90% of the cases. An estimated one out of every four people with diabetes has the disease and does not know it. Knowing their risk for type 2 diabetes helps patients take steps toward prevention. Book places emphasis on Patho-physiology of diabetes and its complications and use of research methodology for accurate results .it comprises clearly understandable, illustrative diagrams and tables for easy adaptability and reproducibility This book contains an amalgamation of the essentials of basic and advanced knowledge of Diabetic and its Complication.
Of all the complications which arise from diabetes, cardiovascular complications are by far the most prevalent and the most deadly. Authored by some of the world's leading names in this area, this outstanding book provides all those managing diabetic patients with clinical, practical and succinct guidance to the diagnosis and management of cardiovascular complications in diabetes. With a joint endocrinology and cardiology focus, and with the very latest in clinical guidelines from the ADA, EASD, AHA, ASC and ESC, selected highlights include: – The role of new biomarkers of cardiovascular disease in diabetes – The latest on diagnosis of cardiovascular problems via vascular imaging – Hypertension and cardiovascular disease in the diabetic patient – Dyslipidaemia and its management in type 2 diabetes – Management of thrombosis, acute coronary syndrome and peripheral arterial disease in diabetes Key points, case studies and self-assessment questions allow for rapid-reference, quick understanding of all topics, thus ensuring that this is perfect reading for endocrinologists, diabetes specialists and cardiologists of all levels managing patients with diabetes and associated cardiovascular problems.
Diabetes mellitus (DM) is becoming a major public health problem, especially now that a large proportion of health care expenditure is being spent on the treatment of this disease and its complications. This was a prospective observational study of diabetes type 2 patients with the objectives of assessing the treatment modalities, glycaemic control and the factors associated with the development of macro and microvascular complications, and evaluating the direct medical costs of treating diabetic type 2 patients at the Hospital Universiti Sains Malaysia (HUSM). All of the type 2 diabetes patients who attended and were followed-up at the HUSM diabetes clinic were included in this study.
Because of the distribution of diabetes mellitus and the little studies that concerns by subjects suffer from diabetes mellitus especially type II and relationship with gastrin hormone in Iraq, so this study was assed the effect of the long term glycemic control by measuring glycosylated hemoglobin (HbA1c), BMI, lipid profile and to find the risk factors for developing microalbuminuria and consequence nephropathy in patients with type II diabetes, also to find the effects of diabetic mellitus type II on the levels of gastrin and thyroid hormones.
Foot problems in diabetic patients are some of the most challenging complications to treat, due to an often quite late presentation of symptoms from the patient. Therefore visual recognition of presenting clinical signs is absolutely key for a successful diagnosis and subsequently, the right management programme. The 3rd edition of Managing the Diabetic Foot once again provides a practical, handy and accessible pocket guide to the clinical management of patients with severe feet problems associated with diabetes, such as ulcers, infections and necrosis. By focusing on the need for a speedy response to the clinical signs, it will enable doctors make rapid, effective management decisions in order to help prevent deterioration and avoid the need for evental foot amputation. Each chapter focuses specifically on the different stages of foot disease and the clinical management required at that particular stage, ie, the normal foot; high-risk foot, ulcerated foot, infected foot, necrotic foot and unsalvageable foot. Full colour throughout, it will feature over 150 clinical photos, numerous hints and tips to aid rapid-reference, as well as the latest national and international guidelines on diabetic foot management. Managing the Diabetic Foot, 3E, is the ideal go-to clinical tool for all diabetes professionals, specialist diabetes nurses and podiatrists managing patients with diabetic foot problems.
Diabetes mellitus is a complex metabolic disease associated with peripheral and central complications. These complications include retinopathy, nephropathy and neuropathy. Several investigations have confirmed the role of oxidative stress in developmental diabetic mediated disorders, possibly via the formation of free radicals . Chronic antioxidant therapies may be useful in decreasing the risk of diabetic complications, from these antioxidants coenzyme Q10 which acts as an antioxidant, inhibiting lipid peroxidation and scavenging free radicals. This study aimed to investigate the brain oxidative stress induced by STZ in rats with consequent changes in brain neurotransmitters and examined the potential protective role of coenzyme Q10 (CoQ10) against the changes STZ induced. Our results cleared that coenzyme Q 10 seems to be a highly promising compound in protecting the diabetic rats against oxidative damage and preventing brain complications such as elevation of neurotransmitters.
The effectiveness of Herbal Medicines on the Management of Diabetes Mellitus Type1 in Goma City, DRC