the effect of biological factors on bone healing in implant dentistryпокупайте товары для здоровья и красоты в интернет-магазине Salonfos.ru:
Current research focuses on parameters that may improve the bone response to oral implants. One of the investigated parameters is the effect of growth factors on bone healing around medical and oral implants. Platelet rich plasma (PRP) is a new approach in tissue regeneration and a developing area for clinicians and researchers. It is used in various surgical fields, including oral and maxillofacial surgery. PRP is prepared out of the patient’s own blood and contains growth factors that influence wound healing. Among them, platelet-derived growth factor (PDGF), transforming growth factor (TGF), insulin-like growth factor (IGF) and epidermal growth factor (EGF) play a pivotal role in tissue repair mechanisms. Although the growth factors and mechanisms involved are still poorly understood, the easy application of PRP in the clinic and its possible beneficial outcome, including reduction of bleeding, rapid soft tissue healing and bone regeneration, holds promise for new treatment approaches. However, animal studies and human trials demonstrate conflicting results regarding the application of PRP. Well-designed studies are needed to provide solid evidence of the PRP capacity.
Successful completion of restorative implant prosthodontics is dependent on the effective implementation of occlusal principles. Occlusion is critical for implant longevity because of nature of attachment of bone to the surface of implant. The ability of bone implant interface to withstand specific ranges of occlusal stress especially during initial loading with the prosthesis is not completely understood. This book emphasizes on the concepts and considerations that should be followed with great precision to achieve successful occlusion in implant dentistry.
The next evolution in titanium implants is likely to be through biologically inspired specific surface modification. This trend in modify surfaces with (bio) chemical moieties that have the potential to induce cell – selective responses, increase bacterial resistance, reduce the risk of inflammation and improve the long–term performance of the implant. The easiest way of immobilizing biological molecules of biological nature on an implant surface is by simply dipping the implant into a solution that contains biological molecules.
This book is a panoramic overview of the factors affecting implant esthetics with special emphasis on prosthodontic management. The idea is to highlight the key factors which make the difference between a surviving & a successful dental implant. With proper understanding of these factors, not only the implantology can become more predictable, but also widen the spectrum of rehabilitation possibilities in dentistry.
This book represent a new challenge in the Laser therapy field. It takes the effect of diode laser on the healing of wound from a molecular level by using immunohistochemical staining technique which represent one of the most advanced method used in histology and pathology. Low Level Laser effect on the biological tissue still need for further studies and by using immunohistochemistry the answers of many questions could be found.
Appropriate loading on dental implant is one of the important factors for long term success of implant prosthesis. Implant-bone interface can easily tolerate the physiological limit of compressive force in a better way than the tensile and shear force. A proper occlusal scheme can eliminate the tensional and shear stresses develop at the implant bone interface under masticatory load and can lengthen the longevity of the implant prosthesis. However the immediate and early loading of dental implant helps to develop a strong implant bone interface with the formation of mature laminar bone. Therefore to get a strong implant bone interface and to reduce the crestal bone loss, the proper occlusal scheme and occlusal loading at correct time is essential. This book emphasizes the different protocol for loading of dental implant prosthesis.
Predictable formation of a direct bone-to-implant interface is a treatment goal in implant dentistry. For this purpose, the existence of appropriate bone quality and quantity is necessary and important. Sufficient alveolar bone volume and favorable architecture of the alveolar ridge are essential to obtain ideal functional and esthetic prosthetic reconstruction following implant therapy. However, unfavorable conditions leading to loss of alveolar bone may render implant placement difficult. The use of barrier membranes for the regeneration of bone defects has significantly changed implant dentistry and the procedure of guided bone regeneration had gained wide popularity amongst clinicians. There have been major advancements since the original expanded polytetrafluoroethylene membranes. Synthetic and natural biomaterials have been used and their mechanical proper-ties and degradation rates are being improved constantly.
Implant placement immediately after extraction followed by an immediate provisional restoration can be a very rewarding way to provide implant therapy to our patients .It provides significant benefit both to the patient and the dentist compared with traditional delayed protocol of waiting for 6 months . It results in an improved preservation of the soft tissue drape and the bone architecture compared with their collapse after tooth extraction.In selected situations,it can even result in avoidance of bone augmentation and soft tissue grafts .The procedure also reduces the number of surgeries which may be beneficial both to the dentist and the patient .Factors critical to success include good initial implant primary stability in good quality bone. However ,immediate implant placement is technically challenging and should only be undertaken by clinicians with considerable experience with implant dentistry , both surgically and prosthetically.
The study of bone fracture and healing is a very challenging job in orthopedic surgery. In the present perspective of this endeavor is to document of ever increasing growth factors and their respective roles to get a successful repaired bone. Therefore the present study envisage the healing of bone fractures and the role of growth factors like TGF-?1, IGF-1, FGF, PDGF, VEGF and bone morphogenetic proteins-2 and 7 in healing mechanism. In this book a comparative efficacy of TGF-?1, IGF-1 and the combined application of TGF-?1 and IGF-1 was evaluated in augmentation of segmental bone healing. We observed that the combined application of TGF-?1 and IGF-1 stimulated the production of osteoblasts that transformed into osteocytes produced synergistic osteoinductive effect in augmentation of fracture healing and remodeling process in combo group as compared to apply singly. I want to express my sincere wishes to Dr. S. Sarkar and Prof. Subhashis Biswas for their inspiring attitude that increased the strength for such work. Finally I want to express my sincere gratitude to my wife Sipra and son Himanish for their constant support.
Continued high success rate achieved with osseointegrated dental implants is the appropriate result of changes in traditional prosthetic restorations.It is now said that an implant is regarded as osseointegrated when there is no progressive relative movement between the implant and the bone with which it has direct contact.The success of the implant depends upon its osseointegration with the surrounding bone.Delayed loading is a two-stage procedure with submerged implant-loading after 3-6 months of initial healing and is more critical for lesser bone densities because they are several times weaker than those with significant cortical bone.During the last 20 years authors have reported that root form implants may osseointegrate, even though they extend above the bone and through the soft tissues during early bone remodeling.Immediate loading not only includes a non submerged one stage surgery but actually loads the implant with the provisional restoration at the same appointment.This book explains in detail about osseointegration of dental implants, factors associated and in detail about the delayed and immediate loading protocols of implant dentistry.
Occlusion is an imperial factor in success of restoration, as the design of the restoration can utilize occlusal forces constructively. The occlusal forces in implant dentistry includes the transosteal forces, bone biomechanics, basic biomechanics, differences in natural teeth and implants, muscles of mastication and occlusal forces and bone resorption. In addition systematic individual treatment plans and precise surgical prosthodontic procedures based on biomechanical principles are pre requisite for optimal implant occlusion.
Aggressive periodontitis poses a great challenge to clinicians with regards to stabilization of periodontal disease and prosthetic rehabilitation. Implant placement in patients diagnosed with aggressive periodontitis is often considered "taboo" due to the multiple complicating factors of this disease and the rapid nature of destruction of the periodontal attachment apparatus. The preprosthetic implant site preparation is the most important, but most often overlooked procedure in implant dentistry. This book has been written with the sole aim of encouraging the implant practitioners in providing an esthetic and functioning dentition for such patients by performing the most valued step of pre-prosthetic site preparation to achieve fine quality and quantity of bone for implant placement.
Hydroxyapatite (HAp) is the emerging bioceramic, which is widely used in various biomedical applications, mainly in dentistry. Hydroxyapatite has excellent biological behavior and its composition and crystal structure is same as apatite in human dental structures and skeletal system. It possesses exceptional biocompatibility and unique bioactivity. It has been widely used in hard tissue replacement and reconstruction applications, such as implant coatings, and bone substitues etc. Incorporation of hydroxyapatite into various restorative materials was found to improve mechanical properties of material without impeding their inherent biological properties
Occlusion is one of the critical factors for long term success of dental implant. The lack of proprioceptive receptor in osseo-intergrated implants, is one of the major reasons for over loading and subsequent crestal bone loss. A proper occlusal scheme can eliminate the tensional and shear stresses developed at the implant bone interface under masticatory load and can lengthen the longevity of the implant prosthesis. However the immediate and early loading of dental implant helps to develop a strong implant bone interface with mature laminar type of bone. This book is a conscious effort made to enhance the knowledge of occlusion in dental implants.
Dental implant surface technologies have been evolving rapidly to enhance a more rapid bone formation on their surface and hold a potential to increase the predictability of expedited implant therapy. Numerous surface modification approaches have been developed for all classes of dental implants to modulate biological responses and improve the osseointegration and primary stability. Hence, Implant threads should be designed to maximize the delivery of optimal favorable stresses while minimizing the amount of extreme adverse stresses to the bone implant interface. In addition, using of biomaterial coating of implant surface for the enhancement of bone formation has been achieved through the modulation of osteoblasts adhesion and spreading that induced better stability and more implant surface contact area.