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Supplementation of omega-3 fatty acids is very effective in reducing oxidative stress through the improvement of antioxidant enzymes activities . Fish and flaxseed oils are nutritional supplements have a high concentration of omega-3 fatty acids.Flax seed oil is rich in alpha linolenic acid (ALA) while fish oil is rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In this study we aimed to compare the effects of flaxseed and fish oils in reducing oxidative stress especially in attenuating DNA damage through the evaluation of urinary 8-hydroxyguanosine (8-OHdG) in experimental diabetes. The main finding in our study was the reduction of urinary isoprostanes and 8-OHdH , in addition to the reduction of insulin resistance during diabetes. In conclusion, flaxseed and fish oils administration has a potential effect on decreasing insulin resistance in diabetic rats through the scavenging of free radicals and increasing superoxide dismutase . This study also concluded that ,fish oil was more effective than flaxseed oil.
Omega-3 fatty acids are quite beneficial for human health. These play a vital role in lowering blood cholesterol, blood triglycerides and, hence, blood pressure. Omega-3 fatty acids are helpful in preventing heart diseases, skin diseases and auto immune disorders. The daily intake of 0.5 to 1.0 gram omega-3 fatty acids is recommended for an individual for a healthy life. The food industry is taking steps to return these healthful fatty acids to the human diets. In this regards, poultry meat and eggs can serve the purpose if enriched with omega-3 fatty acids. Laying hens have the ability to absorb and deposit dietary fatty acids without considerable modification in the composition. Thus, the lipid metabolism in the hens permits the fortification of eggs with omega-3 fatty acids by dietary supplementation to increase the provision of these fatty acids which are appropriate for human consumption. This book provides the necessary information about the enrichment of eggs with omega-3 fatty acids by supplementing linseed oil and canola oil to the diets of laying hens. These oils are rich sources of omega-3 fatty acids and readily promote the deposition of omega-3 fatty acids in the eggs.
Flaxseed oil is obtained from the seeds of the flax plant (Linum usitatissimum, L.). Flaxseed oil contains both omega-3 and omega-6 fatty acids, which are needed for health. Flaxseed oil contains the essential fatty acid alpha-linolenic acid (ALA), which the body converts into eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), the omega-3 fatty acids found in fish oil. Some researchers think that flaxseed oil might have some of the same benefits as fish oil. Omega-3 fatty acids, usually from fish oil, have been shown to reduce inflammation and help prevent certain chronic diseases such as heart disease and arthritis. The present work elucidate the different pharmacological activities of Flaxseed oil, usually claimed for fish oil. However, authors also observed significant antiulcer activity of Flaxseed oil along with anti-inflammatory activity, an unusual phenomenon for anti-inflammatory drugs.
Supplementation with Omega-3 Fatty Acids has been proposed to reduce the risk of preeclampsia, but the effects of this intervention are still uncertain. Aim: The aim of this study is divided into two parts: 1) to analyze previous studies related to supplementation of omega-3 fatty acids and occurrence of preeclampsia utilizing systematic review approach and 2) to examine the impact of a nutritional protocol of omega-3 fatty acids on the occurrence of preeclampsia among high risk pregnant women (randomized controlled trial). Design: A combination of two designs was used for this study, a systematic review of previous studies as well as a randomized controlled trail. Setting: The randomized controlled trial was conducted at antenatal outpatient, El Manial University hospital. In addition to, delivery ward (section 10) and post natal unit in the department of obstetrics and gynecology. Sample: Concerning sample characteristics among the included studies, all were healthy pregnant women with risk factors for developing preeclampsia and not diagnosed with any medical disorder.
The application of Matrix-Assisted Laser Desorption/Ionisation (MALDI-MS) in the analysis of compounds in various matrices is one which is increasingly becoming popular due to the versatility of the technique i.e. it can be used to investigate a variety of analytes, including most biomolecules. However, optimization of the procedure is highly recommended and often necessary when dealing with the identification or profiling of analyte mixtures, especially with analytes which are present in a similar mass-to-charge region with the matrix (or matrices) used for the analysis. This book highlights the importance of optimization in MALDI-MS for the successful detection of the fatty acids in fish oil mixtures. Here, this technique was utilized for the optimization of analytical parameters and sample preparation methods for the detection of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) poly-unsaturated fatty acids contained in generic omega-3 fish oil capsules.
Over the years, heavy metal pollution has continued to cause instability to aquatic ecosystems. The pollution is mostly from anthropogenic sources like mining activities, sewage treatment plants and non point sources such as agriculture. Lake Victoria being the largest fresh water lake in Africa, has suffered a lot of pollution emanating from the aforementioned sources. The lake plays a major economic role in the economies of the riparian nations especially from fishing. Fish is the major source of polyunsaturated fatty acids (PUFAs) such as omega – 3 and omega – 6 which are very beneficial to human body. Once an aquatic environment is polluted with heavy metal pollutants, it may lead to high intake of the pollutants by the fish hence lowering the levels of the essential fatty acids. This study was carried out so as to investigate if there was any impact of heavy metal pollutants on the types and levels of omega -3 in tilapia fish and also in microalgae which is the basic food of the fish. The results showed presence of heavy metal pollutants in water, sediments, microalgae and fish. Tilapia fish was found to have high proportions of PUFAs which have numerous benefits in the body.
This book reports on studies in the Nutritional Science, that have been conducted from an evolutionary prospective. We illuminate the basic principles of Evolutionary Medicine, that predicts that many, if not all, diseases of civilization are caused by a mismatch between our rapidly changing environment and our ancient genome. We are currently dealing with a conflict between our man-made environment and our genome, which for the greatest part still resides in the Paleolithic era (2.5 million years - 10.000 years ago). There is good evidence that a great part of our evolution occurred in locations where the land meets the water. Our diet is an important part of our environment and insight into the nutritional status of traditionally living populations might consequently provide us with important information that could be of use in both Public Health and Health Care. In this study we focused on two nutrients of which the status is likely to have become jeopardized by our current Western lifestyle. These are the essential fatty acids, notably the long-chain polyunsaturated fatty acids (LCP), and vitamin D, which are both abundantly available in the land-water ecosystem.
The aim of this book is to present the clinical and radiographic assessment of the effect of Omega-3 fatty acids, as an adjunctive therapy in management of chronic periodontitis in postmenopausal osteoporotic females. The patients were divided into 2 groups: the control group received Rutin and vitamin C once daily. The Omega-3 group received Rutin and vitamin C once daily in addition to Omega-3 once daily too. Clinical assessment was done by measuring the plaque index (PI), bleeding on probing index (BOP), pocket depth (PD) and clinical attachment level (CAL)at baseline before administration of the different medications and performing scaling and root planing (baseline) and after 6 and 9 months intervals. In addition assessing of the radiographic linear and density measurements was done. It can be concluded that the use of Omega-3 is a beneficial nutritional supplementation in chronic periodontitis management.
Since the first epidemiological studies, carried out in the ’80s, established the protective effect of fish oil against cardiovascular diseases, the interest for fish oil and omega-3 fatty acids has been highly increased as well as the demand of omega-3 enriched products and nutraceuticals. As consequence, the searching of new omega-3 natural sources, the design of competitive fish oil and omega-3 production processes and the development of different strategies for omega-3 incorporation in food products have become important fields of research all over the world. In the last years, the valorisation of fish by-products as a source of omega-3 rich oil has been considered an outstanding strategy to reduce the waste generation and increase the competitiveness in the fish industry. On the other hand, the development of green technologies based on the use of supercritical carbon dioxide has acquired an enormous interest to produce high value compounds such as omega-3 in a eco-friendly way. This book presents an application of supercritical fluids in extraction, concentration and formulation of omega-3 rich oil using fish by-products as a raw material.
As a wide range of n-3 fatty acids in oil and powder form are currently available for food fortification, the fatty acid (FA) composition of mashed potatoes (MP) formulated with extra virgin olive oil (EVOO) was analyzed by gas chromatography and compared with the FA profile of MP subjected to a freeze/thaw cycle. MP samples were enriched with n-3 polyunsaturated fatty acids (PUFA) using different concentrations of ?-linolenic acid (ALA) (22.5, 30, and 45 g/kg) and n-3 docosahexaeonic acid (DHA)/eicosapentaenoic acid (EPA) (5, 6.25, 7.25, and 10 g/kg) to improve product nutritional quality. ALA was much more chemically stable than DHA and EPA. MP with added ALA at 30 and 45 g/kg and with added DHA/EPA at 5, 6.25 and 7.25 g/kg is considered a source of flaxseed and fish oils n-3 FA, respectively, whereas samples enriched with DHA/EPA at 10 g/kg may claim high fish oil n-3 FA content according to European Regulation. The addition of n-3 obtained from microencapsulated flaxseed and fish oils improved the nutritional indicators that define the quality of the fat, producing a healthier product.